Validating a New Definition for Respiratory Failure in Children

Posted by George Alexander on Friday, October 26th, 2018 at 7:22am.

AP Article link

"According to a first-of-its-kind international study, a new definition of Pediatric Acute Respiratory Distress Syndrome (PARDS) results in a more accurate diagnosis of many more children with the rapidly progressive disease than the widely used adult definition...The study represents the largest-ever international cohort of children with PARDS. A total of 700 patients were studied in 145 pediatric intensive care units (PICU) in 27 countries...

...There were 287 collaborators involved with the study, representing 27 countries. Other authors included: Jeni Kwok, Rica Morzov and Margaret Klein, CHLA; Christopher J.L. Newth, CHLA and USC; Analia Fernandez, Hospital General de Agudos, Argentina; Philippe Jouvet, Sainte Justine Children’s Hospital, Canada; Martin C.L. Kneyber, Beatrix Children’s Hospital, Netherlands; Jon Lillie, Evelina London Children’s Hospital, England; Yolanda M. Lopez-Fernandez, Hospital Universitario Cruces, Spain; Lincoln Smith, University of Washington/Seattle Children’s Hospital; Neal J. Thomas, Penn State Children’s Hospital; Douglas Willson, Children’s Hospital of Richmond, Virginia; and Nadir Yehya, Children’s Hospital of Philadelphia...

...The study was supported by the USC Clinical Translational Science Institute, CHLA Department of Anesthesiology and Critical Care Medicine, Sainte Justine Children’s Hospital, University of Montreal, Canada; and the Respiratory Health Network of Quebec, Canada."

Congratulations to all investigators and sites. Special thanks to participating PALISI members, participating PALISI Executive Committee Members, and participating PALISI Sites for collaborating on this groundbreaking international collaborative research.

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